Alcohols and polyols
- (1)
- (55)
- (347)
- (41)
- (4)
- (8)
- (7)
- (55)
- (3)
- (7)
- (18)
- (1)
- (4)
- (155)
- (1)
- (63)
- (28)
- (14)
- (3)
- (1)
- (1)
- (10)
- (3)
- (2)
- (2)
- (1)
- (1)
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- (1)
- (1)
- (1)
- (6)
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- (30)
- (4)
- (20)
- (10)
- (2)
- (10)
- (4)
- (5)
- (399)
- (6)
- (102)
- (22)
- (50)
- (31)
- (62)
- (13)
- (14)
- (1)
- (2)
- (1)
- (25)
- (6)
- (4)
- (1)
- (6)
- (1)
- (463)
- (9)
- (46)
- (10)
- (46)
- (6)
- (1)
- (6)
- (13)
- (148)
- (114)
- (8)
- (5)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (4)
- (7)
- (14)
- (2)
- (1)
- (6)
- (5)
- (1)
- (12)
- (21)
- (5)
- (2)
- (2)
- (2)
- (16)
- (2)
- (30)
- (1)
- (4)
- (1)
- (2)
- (1)
- (20)
- (10)
- (4)
- (15)
- (1)
- (4)
- (6)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (3)
- (1)
- (28)
- (29)
- (7)
- (3)
- (5)
- (1)
- (36)
- (5)
- (4)
- (2)
- (5)
- (4)
- (17)
- (14)
- (4)
- (5)
- (1)
- (2)
- (5)
- (1)
- (4)
- (37)
- (4)
- (2)
- (6)
- (8)
- (2)
- (2)
- (8)
- (7)
- (7)
- (2)
- (1)
- (1)
- (26)
- (1)
- (1)
- (1)
- (2)
- (1)
- (3)
- (4)
- (2)
- (1)
- (14)
- (12)
- (1)
- (3)
- (2)
- (7)
- (12)
- (1)
- (14)
- (24)
- (1)
- (8)
- (4)
- (1)
- (2)
- (1)
- (22)
- (2)
- (6)
- (5)
- (2)
- (1)
- (5)
- (3)
- (4)
- (24)
- (5)
- (3)
- (5)
- (14)
- (1)
- (1)
- (1)
- (11)
- (3)
- (2)
- (4)
- (11)
- (2)
- (6)
- (4)
- (1)
- (3)
- (6)
- (11)
- (5)
- (4)
- (1)
- (2)
- (11)
- (14)
- (7)
- (2)
- (3)
- (1)
- (3)
- (1)
- (2)
- (1)
- (10)
- (1)
- (2)
- (4)
- (4)
- (1)
- (3)
- (1)
- (3)
- (5)
- (1)
- (1)
- (2)
- (1)
- (10)
- (2)
- (2)
- (3)
- (7)
- (1)
- (1)
- (5)
- (4)
- (1)
- (2)
- (9)
- (4)
- (2)
- (12)
- (4)
- (1)
- (5)
- (4)
- (10)
- (2)
- (5)
- (1)
- (1)
- (1)
- (10)
- (6)
- (1)
- (2)
- (2)
- (6)
- (14)
- (2)
- (4)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (4)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
- (4)
- (3)
- (1)
- (4)
- (5)
- (1)
- (4)
- (5)
- (9)
- (1)
- (5)
- (5)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (5)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (4)
- (2)
- (1)
- (2)
- (2)
- (11)
- (9)
- (1)
- (1)
- (2)
- (1)
- (1)
- (3)
- (1)
- (1)
- (10)
- (1)
- (1)
- (1)
- (2)
- (4)
- (11)
- (1)
- (2)
- (4)
- (20)
- (21)
- (2)
- (8)
- (2)
- (3)
- (3)
- (1)
- (8)
- (4)
- (2)
- (1)
- (1)
- (3)
- (1)
- (2)
- (3)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (5)
- (12)
- (10)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (4)
- (1)
- (1)
- (1)
- (7)
- (2)
- (1)
- (2)
- (1)
- (1)
- (5)
- (4)
- (3)
- (1)
- (1)
- (4)
- (6)
- (1)
- (1)
- (1)
- (5)
- (1)
- (1)
- (4)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (1)
- (1)
- (1)
- (1)
- (1)
- (3)
- (1)
- (2)
- (1)
- (2)
- (2)
- (5)
- (2)
- (1)
- (1)
- (1)
- (1)
- (3)
- (14)
- (1)
- (1)
- (2)
- (1)
- (2)
- (2)
- (4)
- (1)
- (1)
- (4)
- (5)
- (2)
- (2)
- (1)
- (10)
- (4)
- (1)
- (9)
- (1)
- (8)
- (1)
- (1)
- (2)
- (2)
- (2)
- (2)
- (5)
- (1)
- (1)
- (1)
- (1)
- (1)
- (2)
- (1)
- (1)
- (2)
- (5)
- (3)
- (4)
- (1)
- (1)
- (3)
- (2)
- (4)
- (1)
- (1)
- (1)
- (1)
- (4)
- (1)
- (5)
- (1)
- (7)
- (1)
- (2)
- (1)
- (7)
- (1)
- (2)
- (1)
- (1)
- (6)
- (1)
- (1)
- (15)
- (2)
- (1)
- (2)
- (1)
- (1)
- (2)
- (6)
- (1)
- (2)
- (2)
- (1)
- (2)
- (1)
- (1)
- (1)
- (3)
- (1)
- (4)
- (2)
- (2)
- (2)
- (1)
- (2)
- (2)
- (2)
- (1)
- (1)
- (2)
- (12)
- (4)
- (2)
- (1)
- (5)
- (1)
- (1)
- (1)
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- (1)
- (2)
- (1)
- (7)
- (2)
- (1)
- (1)
- (2)
- (7)
- (5)
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- (2)
- (1)
- (1)
- (2)
- (3)
- (9)
- (2)
- (1)
- (4)
- (6)
- (9)
- (3)
- (2)
- (1)
- (1)
- (4)
- (3)
- (2)
- (1)
- (4)
- (3)
- (2)
- (7)
- (1)
- (18)
- (16)
- (1)
- (4)
- (2)
- (4)
- (60)
- (5)
- (2)
- (1)
- (1)
- (30)
- (2)
- (2)
- (11)
- (81)
- (12)
- (4)
- (1)
- (3)
- (7)
- (5)
- (1)
- (81)
- (3)
- (378)
- (4)
- (40)
- (21)
- (1)
- (19)
- (1)
- (22)
- (16)
- (1)
- (2)
- (21)
- (2)
- (2)
- (2)
- (1)
- (67)
- (1)
- (1)
- (1)
- (4)
- (8)
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- (2)
- (2)
- (1)
- (1)
- (4)
- (2)
- (3)
- (2)
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- (9)
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- (8)
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- (1)
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- (3)
- (6)
- (3)
- (3)
- (7)
- (2)
- (2)
- (2)
- (7)
- (4)
- (85)
- (1)
- (5)
- (72)
- (3)
- (5)
- (237)
- (4)
- (2)
- (2)
- (21)
- (279)
- (17)
- (1)
- (6)
- (279)
- (28)
- (2)
- (25)
- (2)
- (3)
- (2)
- (2)
- (2)
- (6)
- (3)
- (2)
- (3)
- (48)
- (3)
- (418)
- (6)
- (3)
- (6)
- (5)
- (47)
- (6)
- (3)
- (1)
- (4)
- (21)
- (16)
- (2)
- (4)
- (11)
- (1)
- (8)
- (2)
- (731)
- (11)
- (3)
- (4)
- (2)
- (9)
- (1)
- (2)
- (2)
- (66)
- (2)
- (2)
- (18)
- (3)
- (4)
- (33)
- (2)
- (31)
- (39)
- (2)
- (3)
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- (3)
- (4)
- (11)
- (3)
- (2)
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- (4)
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- (2)
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- (8)
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- (2)
- (12)
- (6)
- (2)
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- (1)
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- (1)
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Medchemexpress LLC GW806742X (hydrochloride) | 98.3% | 610.01 | 10 MM * 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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GW806742X hydrochloride is an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor. It binds the MLKL pseudokinase domain with a Kd of 9.3 μM and has activity against VEGFR2 (IC50=2 nM). This compound retards MLKL membrane translocation and inhibits necroptosis. It is for research use only.
- ATP mimetic
- Potent MLKL inhibitor
- Binds MLKL pseudokinase domain
- Activity against VEGFR2
- Retards MLKL membrane translocation
- Inhibits necroptosis
- Inhibits necroptotic death of wild-type mouse dermal fibroblasts (MDFs) in a dose-dependent manner
- Shows inhibition of VEGF induced proliferation of HUVECs with an IC50 of 5 nM
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Melitracen hydrochloride | 10563-70-9 | MFCD00242905 | 99.8% | 327.89 g/mol | C21H26ClN | 1 ML
Small and Specialty Supplier Partner
Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Melitracen hydrochloride is a research-grade small molecule antidepressant and anxiolytic agent supplied for in vitro pharmacology, mechanism-of-action studies, and analytical reference. The material is provided with solubility and stock-solution guidance, and recommended storage conditions for both solid and solution forms.
- High purity of 99.8%.
- CAS number 10563-70-9, formula C21H26ClN, molecular weight 327.89 g/mol.
- Available as solid samples and as a pre-made 10 mM solution (1 mL) in DMSO.
- Soluble in DMSO and water at up to 100 mg/mL; ultrasonic assistance may be required.
- Storage: solid at 4°C; in solution store at -80°C up to 6 months or -20°C up to 1 month.
- Includes stock solution preparation guidance for common concentrations.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | 99.9% | C13H16Cl3NO | 50 MG
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) used in scientific research. It has minimal effect on conjugated dopamine (DA) amounts in superfusates of rat striatum slices. This compound contains an Alkyne group, enabling it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Irreversible and selective inhibitor of monoamine oxidase A (MAO-A)
- Structurally related to Pargyline
- Contains an Alkyne group for copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Azide groups
- Increases nicotine infusions and motivation to obtain nicotine in rats at 2 mg/kg daily for 28 days
- Pretreatment with 1 mg/kg intravenously for 1 hour has little effect on the efflux of conjugated dopamine (DA) and p-tyramine-evoked release of conjugated DA from slices of rat striatum
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Medchemexpress LLC SB-277011 hydrochloride | 215804-67-4 | 99.59% | 475.02 | 50 MG
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SB-277011 hydrochloride is a potent and selective dopamine D3 receptor (D3R) antagonist, demonstrating high oral bioavailability and brain penetrance. It exhibits significant selectivity over other dopamine receptors and possesses an excellent pharmacokinetic profile in rats. This compound has been shown to effectively reverse the effects of quinelorane and reduce cocaine self-administration in preclinical studies.
- Potent and selective D3 receptor antagonist
- High oral bioavailability and brain penetrance
- 80- to 100-fold selectivity over other dopamine receptors
- Excellent pharmacokinetic profile
- Reverses quinelorane effects in nucleus accumbens
- Reduces intravenous cocaine self-administration
- Inhibits basal and cocaine-enhanced locomotion
- Appearance: solid, off-white to light yellow
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Medchemexpress LLC Clorgyline hydrochloride | 17780-75-5 | 99.9% | C13H16Cl3NO | 100 MG
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Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) used in scientific research. It is structurally related to Pargyline. It has little effect on the amounts of conjugated dopamine (DA) in superfusate of slices from rat striatum. It contains an Alkyne group, allowing it to undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. This product is for research use only, not sold to patients.
- Irreversible and selective inhibitor of monoamine oxidase A (MAO-A)
- Used in scientific research
- Structurally related to Pargyline
- Has little effect on conjugated dopamine (DA) in superfusate of slices from rat striatum
- Contains an Alkyne group
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups
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Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 | C24H34ClN5O4S | 5MG
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Yonkenafil hydrochloride is the hydrochloride salt of a selective phosphodiesterase 5 (PDE5) inhibitor supplied for research use. It is provided as a high-purity solid suitable for in vitro and preclinical studies involving PDE5-related pathways, neuroscience, and pharmacology. Typical solvent compatibility includes DMSO; follow the SDS and laboratory safety procedures.
- High purity suitable for research.
- Solid form for accurate weighing and formulation.
- Soluble in DMSO for assay preparation.
- Appropriate for in vitro and preclinical pharmacology studies.
- Available in small-scale vials for dose-ranging experiments.
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Medchemexpress LLC Pirlimycin hydrochloride | 78822-40-9 | MFCD27952783 | 99.1% | 447.42 g·mol⁻¹ | C17H32Cl2N2O5S | 1 MG
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Pirlimycin hydrochloride is a lincosamide-class antibiotic supplied as the hydrochloride salt for research use. It inhibits bacterial protein synthesis by binding the 50S ribosomal subunit and is primarily active against Gram-positive organisms. The material is provided as a solid at high purity for analytical and laboratory applications.
- Lincosamide antibiotic.
- Inhibits bacterial protein synthesis via 50S ribosomal binding.
- Primarily active against Gram-positive bacteria.
- High purity (99.1%).
- Supplied as a solid suitable for analytical use.
- Available in small-scale quantities for research.
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Medchemexpress LLC Embramine hydrochloride | 13977-28-1 | 384.74 | 5 MG
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Embramine hydrochloride is a monoethanolamine compound that functions as an antihistamine and anticholinergic. It is intended for research use only.
- Functions as an antihistamine
- Functions as an anticholinergic
- Monoethanolamine compound
- For research use only
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Medchemexpress LLC Sri-37330 hydrochloride | 2322245-49-6 | 99.72% | C16H20ClF3N4O2S | 1 G
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.
- Inhibits human TXNIP promoter activity in INS-1 cells.
- Decreases TXNIP mRNA and protein levels in INS-1 cells.
- Blocks polymerase II binding to the E-box motif of the TXNIP promoter.
- Reduces glucagon secretion in TC1-6 cells.
- Inhibits glucagon-induced glucose output from primary hepatocytes.
- Decreases glucagon secretion and action, and blocks hepatic glucose output in vivo.
- Well tolerated in male C57BL/6J mice.
- Reverses obesity- and STZ-induced diabetes and hepatic steatosis in mice.
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Medchemexpress LLC Alosetron hydrochloride | 122852-69-1 | MFCD03453647 | 99.6% | 10 MG
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Alosetron hydrochloride is a potent, selective 5-HT3 receptor antagonist provided for research use in studies of irritable bowel syndrome and visceral nociception. It is supplied as a high-purity solid and is also available as ready-to-use 10 mM solutions for laboratory assays.
- Potent and selective 5-HT3 receptor antagonist.
- Used in research on diarrhea-predominant irritable bowel syndrome and visceral nociception.
- High purity suitable for analytical and in vitro applications.
- Available as a solid and as pre-made 10 mM solutions for convenience.
- Characterization includes CAS 122852-69-1 and molecular weight 330.81 g/mol.
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Medchemexpress LLC 2(1H)-Isoquinolineacetamide, 3,4-dihydro-6,7-dimethoxy-N-methyl-a-phenyl-1-[2-[4-(trifluoromethy | 913358-93-7 | MFCD22419385 | 100.0% | 549.02 g/mol | C29H32ClF3N2O3 | 25 MG
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Almorexant hydrochloride is the hydrochloride salt of a potent, orally active dual orexin (OX1/OX2) receptor antagonist used in neuroscience research of sleep and arousal mechanisms. It is supplied as a high-purity solid and as a DMSO solution, with batch COA documentation for research use.
- Potent dual orexin receptor antagonist suitable for receptor pharmacology studies
- High purity suitable for in vitro and in vivo experiments
- Available in multiple solid pack sizes and as a DMSO solution
- Certificate of analysis provided for batch-specific quality assurance
- Hydrochloride salt form for improved handling and formulation stability
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Medchemexpress LLC SRI-37330 hydrochloride | 2322245-49-6 | 99.7% | C16H20ClF3N4O2S | 25 MG
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SRI-37330 hydrochloride is an orally bioavailable thioredoxin-interacting protein (TXNIP) inhibitor. It inhibits glucagon secretion and function, reduces hepatic glucose production, and reverses hepatic steatosis. This compound can be used for type 2 diabetes research.
- Inhibits activity of human TXNIP promoter in INS-1 cells.
- Decreases mRNA and protein levels of TXNIP in INS-1 cells.
- Inhibits polymerase II (Pol II) binding to the E-box motif region of the TXNIP promoter.
- Lowers glucagon secretion in TC1-6 cells.
- Inhibits glucagon-induced glucose output from primary hepatocytes.
- Decreases glucagon secretion and action in mice.
- Blocks hepatic glucose output in mice.
- Reverses obesity- and streptozotocin-induced diabetes and hepatic steatosis in mice.
- Well tolerated in male C57BL/6J mice.
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Medchemexpress LLC Sevelamer hydrochloride | 152751-57-0 | 98.0% | 186.08 (monomer) | 5 G
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Sevelamer hydrochloride is an orally active phosphate binding agent primarily used for research related to hyperphosphatemia in chronic kidney disease. This compound consists of polyallylamine crosslinked with epichlorohydrin, and is intended for research use only, not for patient treatment.
- Orally active phosphate binding agent
- Used for research of hyperphosphatemia with chronic kidney disease
- Composed of polyallylamine crosslinked with epichlorohydrin
- Decreases serum levels of gut-derived uremic toxins (such as IAA) in vitro
- Reduces serum phosphate levels in Npt2b-deficient mice in vivo
- Leads to a significant decrease in osteoclast number in uremic WT mice
- Store at 4°C sealed, away from moisture for solid form
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Medchemexpress LLC Slp7111228 hydrochloride | 1449768-48-2 | 98.0% | 5 MG
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SLP7111228 hydrochloride is the hydrochloride salt of SLP7111228 supplied as a solid research reagent for biochemical assay use. It has formula C22H34ClN5O, molecular weight 419.99, and CAS 1449768-48-2. Store sealed at -20°C; in solution store at -80°C for long-term stability.
- Hydrochloride salt form.
- Solid, white/off-white appearance.
- Molecular formula C22H34ClN5O.
- Molecular weight 419.99.
- CAS number 1449768-48-2.
- Storage: -20°C; in solvent -80°C (6 months), -20°C (1 month).
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Medchemexpress LLC Yonkenafil hydrochloride | 804519-64-0 | 99.4% | 524.08 g/mol | C24H34ClN5O4S | 25MG
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Yonkenafil hydrochloride is a research-grade phosphodiesterase 5 (PDE5) inhibitor intended for preclinical and biochemical studies. The compound is supplied as a hydrochloride salt, with molecular formula C24H34ClN5O4S and molecular weight 524.08 g/mol. It is typically used as a reference or test compound in pharmacology and neurobiology research where PDE5 modulation is of interest.
- PDE5 inhibitor suitable for biochemical and cellular assays.
- Reported high purity (99.4%) for consistent experimental results.
- Available in small milligram pack sizes for assay development.
- Hydrochloride salt form for improved handling and stability.
- Molecular properties provided for formulation and dosing calculations.
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